Dr. Denise Hien Awarded NIDA R01 Grant to Advance Patient-Centered Research on PTSD and Substance Use Disorders
Dr. Denise Hien, Helen E. Chaney Endowed Chair in Alcohol Studies and Distinguished Professor at the Rutgers–New Brunswick Graduate School of Applied and Professional Psychology, has received a new R01 grant from the National Institute on Drug Abuse for her project, “Advancing patient-centered research using meta-analysis of individual patient data to identify clinically significant trajectories of PTSD/SUD and recovery outcomes.” Dr. Hien, along with Rutgers Co-Investigators Dr. Peggy Swarbrick and Dr. Angelo Dibello, are affiliated with both the Center of Alcohol and Substance Use Studies (CAS) and the Rutgers Addiction Research Center (RARC).
This interinstitutional data science project – led by Rutgers and conducted in collaboration with RTI International (Dr. Antonio Morgan-Lopez, Dr. Lissette Saavedra, Dr. Shannon Blakey), The University of California San Diego (Dr. Sonya Norman), the Medical University of South Carolina (Drs. Sudie Back and Therese Killeen), the City College of New York (Drs. Lesia Ruglass and Teresa Lopez Castro), and Yale University (Dr. Ismene Petrakis)- applies innovative statistical approaches, meta-analysis of individual patient data, integrative data analysis, and propensity score weighting, to evaluate the comparative effectiveness of pharmacological, behavioral, and combination treatments for individuals with co-occurring post-traumatic stress disorder (PTSD) and substance use disorders (SUD).
This team aims to uncover how specific treatments impact PTSD symptoms, substance use patterns, and long-term recovery outcomes. Analyzing data from over 60 randomized controlled trials and more than 8,000 participants, the study will provide clinicians with precise, patient-centered insights to better match individuals with treatments most likely to lead to meaningful improvement, while also identifying approaches that may be less effective for certain populations.
Learn more: https://reporter.nih.gov/search/-RgD_cCuuE-axyNl3oIyyw/project-details/11161748
