Funding Opportunities

Each month, we distribute a curated selection of federal (NIH) and non-federal (private and nonprofit) funding opportunities relevant to neuroscience, brain health, and mental health research. Below are the featured RFAs for June 2025. Use the search box to filter by keyword.

NIH Funding Opportunities

TitleRelease DateExpired DateActivity CodeOrganizationDocument NumberURL
Ex Vivo Models for Studies at the Intersection of HIV and Addictive Substance Use (R01 Clinical Trial Not Allowed)12/30/20248/14/2025R01NIDARFA-DA-25-074https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-074.html
Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV (R61/R33 Clinical Trial Not Allowed)8/23/20248/15/2025R61/R33NIDARFA-DA-25-063https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-063.html
Exploratory Studies to Investigate Mechanisms of HIV infection, Replication, Latency, and/or Pathogenesis in the Context of Substance Use Disorders (R01 Clinical Trial Not Allowed)9/9/20248/15/2025R01NIDARFA-DA-25-073https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-073.html
Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)9/9/20229/26/2025R24ORIPRFA-OD-22-013https://grants.nih.gov/grants/guide/rfa-files/RFA-OD-22-013.html
Alzheimer’s Disease Research Centers (P30 Clinical Trial Not Allowed)1/11/20239/27/2025P30NIARFA-AG-24-001https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-24-001.html
Research Opportunities in Crisis Response Services for Suicide Prevention (R01 Clinical Trial Optional)6/13/202410/9/2025R01NIMHRFA-MH-25-135https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-135.html
Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional)10/30/202410/21/2025R01NIMHRFA-MH-25-205https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-205.html
Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional)10/30/202410/21/2025R21NIMHRFA-MH-25-206https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-206.html
Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required8/14/202410/24/2025R01FDARFA-FD-25-001https://grants.nih.gov/grants/guide/rfa-files/RFA-FD-25-001.html
BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)9/24/20241/21/2026R01NINDSRFA-NS-25-018https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-018.html
BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)9/24/20241/21/2026U01NINDSRFA-NS-25-017https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-017.html
Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)9/28/20233/14/2026R43/R44NIDARFA-DA-25-048https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-048.html
Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)9/28/20233/14/2026R41/R42NIDARFA-DA-25-047https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-047.html
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R21 Clinical Trial Not Allowed)8/14/20243/20/2026R21NIDARFA-DA-26-002https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-002.html
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)8/14/20243/20/2026R01NIDARFA-DA-26-001https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-001.html
BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)12/9/20246/16/2026R21NEIRFA-EY-25-001https://grants.nih.gov/grants/guide/rfa-files/RFA-EY-25-001.html
BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 – Clinical Trials Not Allowed)11/21/20246/18/2026R34NINDSRFA-NS-25-016https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-016.html
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)2/20/20247/2/2026U24NIMHRFA-MH-25-105https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-105.html
INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)2/22/20247/2/2026F99/K00NICHDRFA-OD-24-007https://grants.nih.gov/grants/guide/rfa-files/RFA-OD-24-007.html
BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)11/5/20249/29/2026UH3NINDSRFA-NS-25-022https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-022.html
BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)11/5/20249/29/2026UG3/UH3NINDSRFA-NS-25-021https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-021.html
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 – Clinical Trial Not Allowed)9/18/20241/16/2027R61/R33NINDSRFA-NS-25-023https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-023.html
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 – Clinical Trial Not Allowed)3/19/20241/29/2027R18NINDSRFA-NS-24-031https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-031.html
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)11/15/20242/9/2027R01NIMHRFA-MH-26-170https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-170.html
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)9/26/20246/16/2027U24NIMHRFA-MH-26-120https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-120.html
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)10/23/20246/16/2027U01NIMHRFA-MH-26-140https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-140.html
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)11/20/202411/19/2027R01NIDARFA-DA-26-034https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-034.html
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)12/5/202412/4/2027R21NIDARFA-DA-26-056https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-056.html
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)12/5/202412/4/2027R01NIDARFA-DA-26-055https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-055.html

Private and Nonprofit Funding Opportunities

TitleResearch AreasCareer StageURL
Alpha-Synuclein Imaging PrizeParkinson’s disease, neurodegeneration Early Career and Emerging in Field Graduate Student or Pre-doc Mid-Career to Established in Field Undergraduate Student

https://www.michaeljfox.org/news/alpha-synuclein-imaging-prize

Addressing Violence and Trauma TopicalTraumaNot Applicable

https://www.pcori.org/funding-opportunities/announcement/addressing-violence-and-trauma-topical-pcori-funding-announcement-cycle-2-2025

Molecular MRI Biomarker Programmolecular MRI (mMRI), Parkinson’s disease, Mitochondrial ImpairmentNot Applicable

https://www.michaeljfox.org/grant/molecular-mri-biomarker-program

Rita Allen Foundation ScholarsCancer, immunology, and neuroscience, painEarly Career and Emerging in Field Mid-Career to Established in Field

http://ritaallen.org/scholars/#faq-list

ADDF-Harrington Scholar ProgramAlzheimer’s disease and related dementiasEarly Career and Emerging in Field Mid-Career to Established in Field

http://www.alzdiscovery.org/research-and-grants/funding-opportunities/harrington

Phased Large Awards for Comparative Effectiveness Research (PLACER)Intellectual and Developmental Disabilities, Maternal Morbidity and Mortality, Mental and Behavioral Health, Pain, Rare Diseases, Sensory Impairment, Sleep, Substance Use, Violence and TraumaNot Applicable

https://www.pcori.org/funding-opportunities/announcement/phased-large-awards-comparative-effectiveness-research-pcori-funding-announcement-cycle-2-2025

Fellows-to-Faculty AwardAutism, NeuroscienceEarly Career and Emerging in Field

https://www.simonsfoundation.org/grant/fellows-to-faculty-award/

Neurobiology of Brain Disorders Awardbiological mechanisms of neurological and psychiatric disordersEarly Career and Emerging in Field Mid-Career to Established in Field

https://www.mcknight.org/programs/the-mcknight-endowment-fund-for-neuroscience/neurobiology-of-brain-disorders-award/

Neuroimaging and CSF Biomarker Development ProgramAlzheimer’s disease and related dementias, PET, MRI, EEGEarly Career and Emerging in Field Mid-Career to Established in Field

https://www.alzdiscovery.org/research-and-grants/funding-opportunities/biomarkers

Distinguished Scientist Awardsbrain cancer research, brain tumors/brain cancer. Early Career and Emerging in Field

https://sontagfoundation.org/about-dsa/

McKnight Brain Research Foundation Innovator Awards in Cognitive Aging and Memory Losscognitive aging, memory lossEarly Career and Emerging in Field

https://www.afar.org/grants/mcknight-award

McKnight Brain Research Foundation Innovator Awards in Cognitive Aging and Memory Losscognitive aging, memory lossEarly Career and Emerging in Field

https://www.afar.org/grants/mcknight-award

Neuroscience Investigator AwardsNeuroscienceEarly Career and Emerging in Field

https://nyscf.org/programs/extramural-grants/applicants/neuroscience-investigator-awards/

Improving Mental and Behavioral Health Topicalattention-deficit hyperactivity disorder (ADHD)Not Applicable

https://www.pcori.org/funding-opportunities/announcement/improving-mental-and-behavioral-health-topical-pcori-funding-announcement-cycle-1-2025

Autism Rat Models Consortium – Request for Applicationsautism and related neurodevelopmental disorders (NDD)Not Applicable

https://www.sfari.org/grant/second-autism-rat-models-consortium-rfa/

The Science of Perception Box RFPmental health and wellness in pediatric populationsEarly Career and Emerging in Field Mid-Career to Established in Field

https://www.tinybluedotfoundation.org/rfp

Neuroscience Prizenervous systemEarly Career and Emerging in Field Mid-Career to Established in Field

https://gruber.yale.edu/neuroscience-prize-nomination-criteria

Parkinson’s Disease Translational Research ProgramParkinson’s diseaseNot Applicable

https://sparkns.org/call-for-proposals/