Funding Opportunities

Each month, we distribute a curated selection of federal (NIH) and non-federal (private and nonprofit) funding opportunities relevant to neuroscience, brain health, and mental health research.
Below are the featured RFAs for August 2025. Use the search box to filter by keyword.

 

NIH Funding Opportunities

TitleRelease DateExpiry DateActivity CodeOrganizationDocument NumberClinical TrialsURL
NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional)6/12/20259/10/2025DP1NIHRFA-RM-25-001Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-001.html
Alzheimer’s Disease Research Centers (P30 Clinical Trial Not Allowed)1/11/20239/27/2025P30NIARFA-AG-24-001Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-AG-24-001.html
NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program (RC2 – Clinical Trial Not Allowed)10/31/202410/18/2025RC2NINDSRFA-NS-25-019Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-019.html
Single Source: National Longitudinal Study of Adolescent to Adult (Add) Health Wave VII (U01 Clinical Trial Not Allowed)6/16/202510/18/2025U01NIARFA-AG-26-001Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-AG-26-001.html
National Alzheimers Coordinating Center (U24 Clinical Trial Not Allowed)6/17/202510/18/2025U24NIARFA-AG-26-003Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-AG-26-003.html
Single Source: National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) (U24 Clinical Trial Not Allowed)6/26/202510/18/2025U24NIARFA-AG-26-002Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-AG-26-002.html
Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional)10/30/202410/21/2025R01NIMHRFA-MH-25-205Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-205.html
Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional)10/30/202410/21/2025R21NIMHRFA-MH-25-206Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-206.html
Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required8/14/202410/24/2025R01FDARFA-FD-25-001Requiredhttps://grants.nih.gov/grants/guide/rfa-files/RFA-FD-25-001.html
BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)9/24/20241/21/2026R01NINDSRFA-NS-25-018Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-018.html
BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)9/24/20241/21/2026U01NINDSRFA-NS-25-017Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-017.html
Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R21 Clinical Trials Not Allowed)9/30/20243/11/2026R21NIDARFA-DA-26-010Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-010.html
Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R01 Clinical Trials Not Allowed)9/30/20243/11/2026R01NIDARFA-DA-26-009Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-009.html
Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)9/28/20233/14/2026R43/R44NIDARFA-DA-25-048Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-048.html
Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)9/28/20233/14/2026R41/R42NIDARFA-DA-25-047Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-047.html
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R21 Clinical Trial Not Allowed)8/14/20243/20/2026R21NIDARFA-DA-26-002Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-002.html
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)8/14/20243/20/2026R01NIDARFA-DA-26-001Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-001.html
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)12/6/20246/3/2026R21NCATSRFA-TR-25-002Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-TR-25-002.html
BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)12/9/20246/16/2026R21NEIRFA-EY-25-001Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-EY-25-001.html
BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 – Clinical Trials Not Allowed)11/21/20246/18/2026R34NINDSRFA-NS-25-016Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-016.html
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)2/20/20247/2/2026U24NIMHRFA-MH-25-105Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-105.html
INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)2/22/20247/2/2026F99/K00NICHDRFA-OD-24-007Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-OD-24-007.html
Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional)6/24/20257/15/2026R03NIHRFA-OD-25-008Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-OD-25-008.html
BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)11/5/20249/29/2026UH3NINDSRFA-NS-25-022Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-022.html
BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)11/5/20249/29/2026UG3/UH3NINDSRFA-NS-25-021Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-021.html
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)1/8/202511/24/2026R15NCCIHRFA-AT-25-003Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-AT-25-003.html
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 – Clinical Trial Not Allowed)9/18/20241/16/2027R61/R33NINDSRFA-NS-25-023Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-023.html
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 – Clinical Trial Not Allowed)3/19/20241/29/2027R18NINDSRFA-NS-24-031Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-031.html
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)11/15/20242/9/2027R01NIMHRFA-MH-26-170Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-170.html
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)1/17/20242/12/2027RM1NIDARFA-DA-25-060Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-060.html
High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)8/2/20242/12/2027R01NIDARFA-DA-25-024Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-024.html
NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)4/26/20244/29/2027R35NHLBIRFA-HL-26-003Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-003.html
NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)4/26/20244/29/2027R35NHLBIRFA-HL-26-002Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-002.html
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)9/26/20246/16/2027U24NIMHRFA-MH-26-120Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-120.html
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)10/23/20246/16/2027U01NIMHRFA-MH-26-140Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-140.html
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)12/16/202410/13/2027R01NIDCDRFA-DC-25-002Optionalhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DC-25-002.html
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)11/20/202411/19/2027R01NIDARFA-DA-26-034Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-034.html
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)12/5/202412/4/2027R21NIDARFA-DA-26-056Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-056.html
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)12/5/202412/4/2027R01NIDARFA-DA-26-055Not_Allowedhttps://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-055.html

Private and Nonprofit Funding Opportunities

TitleFunderExpiry DateResearch AreaFunding TypeURL
Rutgers Limited Submission OpportunitiesRutgers University//Rutgers Internal Funding Opportunities and Limited Submissions https://rutgers.infoready4.com/#ored
Esther A. & Joseph Klingenstein Fund: Klingenstein-Simons Fellowship Awards in NeuroscienceKlingenstein Philanthropies 1 Feb 26Neurological and behavioral disorders, Cellular and molecular neuroscience, Neural systems, Translational researchFellowships or Post-doctoral Awards Research: Project Grants & Innovation https://klingenstein.org/esther-a-joseph-klingenstein-fund/neuroscience/applying/
Discovery Research GrantsBreakthrough Discoveries for Thriving with Bipolar Disorder 18 Feb 26bipolar disorder, fundamental mechanisms, heterogeneity, progression, and underlying biologyResearch: Project Grants & Innovation https://www.bipolardiscoveries.org/funding/rfa-opportunities/
The Science of Perception Box RFPTiny Blue Dot Foundation 28 Feb 26neural, experiential, and psychological factors related to Perception Box, mindfulness, breathwork, high-quality listening, psychedelics, neuromodulation, mental health and wellness in pediatric populations aged 5-18Research: Project Grants & Innovation https://www.tinybluedotfoundation.org/rfp
Neuroscience PrizeGruber Foundation Yale University 15 Dec 25Brain, spinal cord, or peripheral nervous systemPrizes and Awards https://gruber.yale.edu/neuroscience-prize-nomination-criteria
MIND (Maximizing Innovation in Neuroscience Discovery) PrizePershing Square Foundation 3 Nov 25neurobiology, brain imaging and mapping, machine learning, drug delivery, and synthetic biologyResearch: Project Grants & Innovation https://prizeapplication.smapply.io/
Autism Rat Models Consortium – Request for ApplicationsSimons Foundation 6 Mar 26Autism and related neurodevelopmental disorders (NDD)Research: Project Grants & Innovation https://www.sfari.org/grant/second-autism-rat-models-consortium-rfa/
Alpha-Synuclein Imaging PrizeThe Michael J. Fox Foundation for Parkinson’s Research (MJFF) No deadlineParkinson’s disease, neurodegenerationPrizes and Awards https://www.michaeljfox.org/news/alpha-synuclein-imaging-prize